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2017年3月-4月最新進(jìn)展

發(fā)布時(shí)間:2017-07-19 瀏覽數:11836次

諾維信和勃林格殷格翰宣布家禽益生菌領(lǐng)域戰略合作

2017年3月30日:勃林格殷格翰動(dòng)物健康部與諾維信宣布將在家禽產(chǎn)品益生菌的研發(fā)和市場(chǎng)銷(xiāo)售領(lǐng)域進(jìn)行戰略合作。雙方將重點(diǎn)關(guān)注孵化場(chǎng)的產(chǎn)品研發(fā)(孵化場(chǎng)即在小雞送往農場(chǎng)之前將蛋孵化出來(lái)的地方)。作為協(xié)議的一部分,勃林格殷格翰將負責諾維信產(chǎn)品FloraMax?在美國家禽市場(chǎng)的推廣和分銷(xiāo)。勃林格殷格翰計劃在未來(lái)幾年中將其推展至全球其他市場(chǎng)。  


Codexis宣布與Tate&Lyle針對食品工業(yè)酶開(kāi)展第二個(gè)多年協(xié)議
2017年3月31日:Codexis宣布就一種食品工業(yè)酶與全球食品配料公司達成第二個(gè)多年協(xié)議。Codexis稱(chēng),這個(gè)新的協(xié)議涵蓋了其公司支持Tate&Lyle食品成分新型酶的研究和開(kāi)發(fā)。根據這個(gè)研發(fā)協(xié)議,針對Codexis之前獨立開(kāi)發(fā)的酶技術(shù)改進(jìn),Tate&Lyle將會(huì )在2017年第二季度的支付給Codexis一筆款;并且在未來(lái)的兩三年中,Tate&Lyle也會(huì )也會(huì )支付固定的研發(fā)服務(wù)費和里程碑費用。另外,Codexis以每股4美元的價(jià)格提供了550萬(wàn)股普通股的二次發(fā)行,扣除費用后估計增加了2020萬(wàn)美元。

 

Amyris宣布與Blue California在中國獨家生產(chǎn)協(xié)議

2017年4月8日:Amyris宣布擴大其與Phyto Tech Corp(D/B/A “Blue California”)的合作關(guān)系范圍。Blue California位于加利福尼亞南部,是全球食品、調料和香料原料與保健品的領(lǐng)導者。


會(huì )議預告

1)2017年5月16日-18日Informex貿易展覽和會(huì )議,賓夕法尼亞州費城,美國;

http://www.informex.com/


2)2017年7月9日-13日,Biotrans 2017,匈牙利布達佩斯;

http://www.biotrans2017.com


最新發(fā)表文獻摘選

Functional expression of a novel α-amylase from Antarctic psychrotolerant fungus for baking industry and its magnetic immobilization.

He L, Mao Y, Zhang L, Wang H, Alias SA, Gao B, Wei D. BMC Biotechnol. 2017 Feb 28;17(1):22. doi: 10.1186/s12896-017-0343-8.

https://www.ncbi.nlm.nih.gov/pubmed/28245836


Encapsulation of enzymes in metal ion-surfactant nanocomposites for catalysis in highly polar solvents.

Cao X, Ni Y, Zhang A, Xu S, Chen K, Ouyang P. Chem Commun (Camb). 2017 Feb 28. doi: 10.1039/c7cc00607a. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28245017


Highly Efficient Enzymatic Acylation of Dihydromyricetin by the Immobilized Lipase with Deep Eutectic Solvents as Cosolvent.

Cao SL, Deng X, Xu P, Huang ZX, Zhou J, Li XH, Zong MH, Lou WY. J Agric Food Chem. 2017 Mar 7. doi: 10.1021/acs.jafc.7b00011. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28244316


Efficient synthesis of (S)-N-Boc-3-hydroxypiperidine using an (R)-specific carbonyl reductase from Candida parapsilosis.

Chen J, Yan M, Xu L. World J Microbiol Biotechnol. 2017 Mar;33(3):61. doi: 10.1007/s11274-016-2189-y.

https://www.ncbi.nlm.nih.gov/pubmed/28243985


Enzyme-Catalyzed Intramolecular Enantioselective Hydroalkoxylation.

Gao SS, Garcia-Borràs M, Barber JS, Hai Y, Duan A, Garg NK, Houk KN, Tang Y. J Am Chem Soc. 2017 Mar 1. doi: 10.1021/jacs.7b01089. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28240554


Computational tools for enzyme improvement: why everyone can - and should - use them.

Ebert MC, Pelletier JN. Curr Opin Chem Biol. 2017 Feb 20;37:89-96. doi: 10.1016/j.cbpa.2017.01.021. [Epub ahead of print] Review.

https://www.ncbi.nlm.nih.gov/pubmed/28231515


Biochemical characterization of the native α-carbonic anhydrase purified from the mantle of the Mediterranean mussel, Mytilus galloprovincialis.

Perfetto R, Del Prete S, Vullo D, Sansone G, Barone C, Rossi M, Supuran CT, Capasso C. J Enzyme Inhib Med Chem. 2017 Dec;32(1):632-639. doi: 10.1080/14756366.2017.1284069.

https://www.ncbi.nlm.nih.gov/pubmed/28229634


Four distinct types of E.C. 1.2.1.30 enzymes can catalyze the reduction of carboxylic acids to aldehydes.

Stolterfoht H, Schwendenwein D, Sensen CW, Rudroff F, Winkler M. J Biotechnol. 2017 Feb 18. pii: S0168-1656(17)30077-9. doi: 10.1016/j.jbiotec.2017.02.014. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28223183


Whole-Cell Biocatalytic Synthesis of Cinnamyl Acetate with a Novel Esterase from the DNA Library of Acinetobacter hemolyticus.

Dong H, Secundo F, Xue C, Mao X. J Agric Food Chem. 2017 Feb 28. doi: 10.1021/acs.jafc.6b05799. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28220703


Purification, characterization, and overexpression of an endo-1,4-?-mannanase from thermotolerant Bacillus sp. SWU60.

Seesom W, Thongket P, Yamamoto T, Takenaka S, Sakamoto T, Sukhumsirichart W. World J Microbiol Biotechnol. 2017 Mar;33(3):53. doi: 10.1007/s11274-017-2224-7.

https://www.ncbi.nlm.nih.gov/pubmed/28220352


Biotechnological Applications of Marine Enzymes From Algae, Bacteria, Fungi, and Sponges.

Parte S, Sirisha VL, DSouza JS. Adv Food Nutr Res. 2017;80:75-106. doi: 10.1016/bs.afnr.2016.10.005.

https://www.ncbi.nlm.nih.gov/pubmed/28215329


Comparison of Biochemical Properties of the Original and Newly Identified Oleate Hydratases from Stenotrophomonas maltophilia.

Kang WR, Seo MJ, Shin KC, Park JB, Oh DK. Appl Environ Microbiol. 2017 Feb 24. pii: AEM.03351-16. doi: 10.1128/AEM.03351-16. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28235876


Structural Basis of the Substrate Specificity and Enzyme Catalysis of a Papaver somniferum Tyrosine Decarboxylase.

Guan H, Song S, Robinson H, Liang J, Ding H, Li J, Han Q. Front Mol Biosci. 2017 Feb 9;4:5. doi: 10.3389/fmolb.2017.00005.

https://www.ncbi.nlm.nih.gov/pubmed/28232911


Simultaneous Enhancement of Bioactivity and Stability of Laccase by Cu(2+)/PAA/PPEGA Matrix for Efficient Biosensing and Recyclable Decontamination of Pyrocatechol.

Chen T, Xu Y, Peng Z, Li A, Liu J. Anal Chem. 2017 Feb 7;89(3):2065-2072. doi: 10.1021/acs.analchem.6b04691.

https://www.ncbi.nlm.nih.gov/pubmed/28208260


Alkane Oxidation: Methane Monooxygenases, Related Enzymes, and Their Biomimetics.

Wang VC, Maji S, Chen PP, Lee HK, Yu SS, Chan SI. Chem Rev. 2017 Feb 16. doi: 10.1021/acs.chemrev.6b00624. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28206744


De novo biosynthesis of pterostilbene in an Escherichia coli strain using a new resveratrol O-methyltransferase from Arabidopsis.

Heo KT, Kang SY, Hong YS. Microb Cell Fact. 2017 Feb 15;16(1):30. doi: 10.1186/s12934-017-0644-6.

https://www.ncbi.nlm.nih.gov/pubmed/28202018


The First Biocatalytic Carbon-Silicon Bond Formation.

Lütz S. Angew Chem Int Ed Engl. 2017 Feb 15. doi: 10.1002/anie.201612543. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28198074


Enzyme Immobilized on Nanoporous Carbon Derived from Metal-Organic Framework: A New Support for Biodiesel Synthesis.

Liu LH, Shih YH, Liu WL, Lin CH, Huang HY. ChemSusChem. 2017 Feb 13. doi: 10.1002/cssc.201700142. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28195433


Conversion of cysteine to 3-mercaptopyruvic acid by bacterial aminotransferases.

Andree?en C, Gerlt V, Steinbüchel A. Enzyme Microb Technol. 2017 Apr;99:38-48. doi: 10.1016/j.enzmictec.2017.01.004.

https://www.ncbi.nlm.nih.gov/pubmed/28193330


A common mechanism for coenzyme cobalamin-dependent reductive dehalogenases.

Johannissen LO, Leys D, Hay S. Phys Chem Chem Phys. 2017 Feb 22;19(8):6090-6094. doi: 10.1039/c6cp08659d.

https://www.ncbi.nlm.nih.gov/pubmed/28191552


Cloning, evaluation, and high-level expression of a thermo-alkaline pectate lyase from alkaliphilic Bacillus clausii with potential in ramie degumming.

Zhou C, Xue Y, Ma Y. Appl Microbiol Biotechnol. 2017 Feb 9. doi: 10.1007/s00253-017-8110-2. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28184988


Strange New World: Bacteria Catalyze Ubiquitylation via ADP Ribosylation.

Komander D, Randow F. Cell Host Microbe. 2017 Feb 8;21(2):127-129. doi: 10.1016/j.chom.2017.01.014.

https://www.ncbi.nlm.nih.gov/pubmed/28182945


Evolution and Distribution of C(7)-Cyclitol Synthases in Prokaryotes and Eukaryotes.

Osborn AR, Kean KM, Alseud KM, Almabruk KH, Asamizu S, Lee JA, Karplus PA, Mahmud T. ACS Chem Biol. 2017 Feb 17. doi: 10.1021/acschembio.7b00066. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28182402


Structural basis for redox sensitivity in Corynebacterium glutamicum diaminopimelate epimerase: an enzyme involved in l-lysine biosynthesis.

Sagong HY, Kim KJ. Sci Rep. 2017 Feb 8;7:42318. doi: 10.1038/srep42318.

https://www.ncbi.nlm.nih.gov/pubmed/28176858


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